Yes, and it is one of the most common day trips in Argentina. Iguazú sits about 1,100 km north of Buenos Aires, which rules out driving and makes flying the only way to see the falls and sleep in your own bed the same night. Each flight is about 1 h 50 m.
The shape of the day: a 4:30 am hotel pickup, a dawn flight north, 7 to 8 hours inside Iguazú National Park, and an evening flight that has you back in the city around 10:25 pm. Roughly 13 hours door to door once the legs are added up.
What has to line up
- A departure before 8 am. Later than that and the day starts shedding circuits
- A return after 7 pm, so the park keeps the whole afternoon
- Transfers waiting at both airports, a taxi that never shows at 4 am costs you the flight
- Park admission bought in advance, so you walk straight through the gates
That is four bookings that all have to hold on the same morning. Arrange them separately and one delay breaks the chain, and there is no second flight to catch and no second day to try again.
What does not fit
The Brazilian side. It needs a day of its own, and for some nationalities a visa. What one day does cover is the three main Argentine circuits, Devil’s Throat, Upper and Lower. That is the bulk of what people travel here to see.